The highly contagious delta variant is the fastest and fittest coronavirus strain yet, and it will "pick off" the most vulnerable people, especially in places with low Covid-19 vaccination rates, World Health Organization officials warned Monday. From a report: Delta, first identified in India, has the potential "to be more lethal because it's more efficient in the way it transmits between humans and it will eventually find those vulnerable individuals who will become severely ill have to be hospitalized and potentially die," Dr. Mike Ryan, executive director of the WHO's emergencies program, said during a news conference. Ryan said world leaders and public health officials can help defend the most vulnerable through the donation and distribution of Covid vaccines. "We can protect those vulnerable people, those frontline workers," Ryan said, "and the fact that we haven't, as Director-General (Tedros Adhanom Ghebreyesus) has said, again and again, is a catastrophic moral failure at a global level." The WHO said Friday that delta is becoming the dominant variant of the disease worldwide. The agency declared delta a "variant of concern" last month. A variant can be labeled as "of concern" if it has been shown to be more contagious, more deadly or more resistant to current vaccines and treatments, according to the health organization.

USA Today reports: Companies like Moderna and Pfizer's partner BioNTech, whose names are familiar from COVID-19 vaccines, are using mRNA to spur cancer patients' bodies to make vaccines that will — hopefully — prevent recurrences and treatments designed to fight off advanced tumors. If they prove effective, which won't be known for at least another year or two, they could be added to the arsenal of immune therapies designed to get the body to fight off its own tumors...

Over the last decade, pharmaceutical companies around the world have been developing new ways to train the body's immune system to fight off tumors, particularly melanoma. They had learned how to remove a brake installed by tumors, unleashing the warriors of the immune system. Ten years ago, only about 5% of people with advanced melanoma survived for five years. Now, nearly half make it that long. Trials of mRNA cancer vaccines aim to boost that number even higher by adding soldiers to the fight... Once a tumor has been largely removed through surgery, a vaccine can help generate new immune soldiers known as T cells... A computer algorithm analyzes the mutations distinct to the cancer cells, looking for ones that trigger the production of T cells, said Melissa J. Moore, Moderna's chief scientific officer, of platform research. So far, she said, Moderna, working with partner Merck, has tested these personalized vaccines in about 100 patients. They aim eventually to make a personalized mRNA vaccine within about 45 days after the patient's cancer surgery, during their recovery...

Mutated cancer cells have proteins on their surface that can be targeted by an mRNA vaccine. For a tumor that has, say, five common mutations, a patient could get a combination of five of these vaccines. On Friday, BioNTech announced it was launching a new trial for this approach, testing it in 120 melanoma patients Europe, the United Kingdom, Australia and the U.S. The new treatment, given in connection with an antibody from Regeneron, is aimed at four tumor-associated antigens. More than 90% of melanoma tumors contain at least one of the four.
The U.S. federal government now lists 29 studies underway or that will be soon investigating mRNA cancer vaccines, according to the article.

And Dr. Stephen Hahn, who had a career as an oncologist before running the Food and Drug Administration from 2019 until early this year, "said he's more optimistic this time because of how much researchers have learned about the role the immune system plays in cancer. 'That gives us an edge to maybe finally get to the place where we need to be.'"

The U.S. government spent more than $18 billion last year funding drugmakers to make a Covid vaccine, an effort that led to at least five highly effective shots in record time. Now it's pouring more than $3 billion on a neglected area of research: developing pills to fight the virus early in the course of infection, potentially saving many lives in the years to come. From a report: The new program, announced on Thursday by the Department of Health and Human Services, will speed up the clinical trials of a few promising drug candidates. If all goes well, some of those first pills could be ready by the end of the year. The Antiviral Program for Pandemics will also support research on entirely new drugs -- not just for the coronavirus, but for viruses that could cause future pandemics. A number of other viruses, including influenza, H.I.V. and hepatitis C, can be treated with a simple pill. But despite more than a year of research, no such pill exists to treat someone with a coronavirus infection before it wreaks havoc. Operation Warp Speed, the Trump administration's program for accelerating Covid-19 research, invested far more money in the development of vaccines than of treatments, a gap that the new program will try to fill.

Dr. Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases and a key backer of the program, said he looked forward to a time when Covid-19 patients could pick up antiviral pills from a pharmacy as soon as they tested positive for the coronavirus or develop Covid-19 symptoms. "I wake up in the morning, I don't feel very well, my sense of smell and taste go away, I get a sore throat," Dr. Fauci said in an interview. "I call up my doctor and I say, 'I have Covid and I need a prescription.'" Dr. Fauci's support for research on antiviral pills stems from his own experience fighting AIDS three decades ago. In the 1990s, his institute conducted research that led to some of the first antiviral pills for H.I.V., "protease inhibitors" that block an essential virus protein and can keep the virus at bay for a lifetime.

California on Friday started offering residents a digital record of their coronavirus vaccinations that they can use to access businesses or events that require proof they got the shots. From a report: The state's public health and technology departments said the new tool allows Californians access to their COVID-19 vaccination records from the state's immunization registry and includes the same information as the paper cards issued by the Centers for Disease Control and Prevention. To access the information, Californians will enter into a state website their name, date of birth and email or phone associated with their vaccine records and they will be asked to create a four-digit PIN. The record will include a QR code that users can save to their mobile phones. With nearly 20 million people fully vaccinated in California and proof of vaccination already required in some circumstances such as travel, state health officials felt there would be demand for the tool, though it remains optional, said Dr. Erica Pan, the state's epidemiologist.

Apple Chief Executive Tim Cook has said the company's greatest contribution to mankind will be in health. So far, some Apple initiatives aimed at broadly disrupting the healthcare sector have struggled to gain traction, according to people familiar with them and documents reviewed by The Wall Street Journal. From the report: Apple has envisioned an audacious plan for healthcare, offering its own primary-care medical service with Apple-employed doctors at its own clinics, according to people familiar with the plan and documents. To test that and other bold healthcare ideas, it took over clinics that catered to its employees and built a team with scores of clinicians, engineers, product designers and others. Today those ambitions, which aren't widely known, have largely stalled as Apple has shifted the focus of its health unit to something it knows well: Selling devices, specifically the Apple Watch, according to people familiar with its strategy.

The new primary-care service hasn't gotten off the ground, people familiar with it say. A digital health app launched quietly this year has struggled to keep users engaged, say people familiar with the app and the documents seen by the Journal. Some employees have raised questions internally about the integrity of health data coming from the company's clinics that has been used to support product development, according to people familiar with their concerns and the documents.

The government in Pakistan's largest province, Punjab, has decided to block SIM cards of unvaccinated citizens, reports the Hindustan Times (one of the largest newspapers in India), citing reports from news agency ANI.
Dr. Rashid, the provincial health minister in Pakistan's Punjab, said that there has been a "considerable decrease" in Covid-19 cases in the province due to mass vaccinations. However, a report compiled by the Punjab primary health department shows that the province still failed to achieve its set target for Covid-19 vaccination, reports ARY News, adding that around 300,000 recipients of the first dose of the vaccine never returned for the second dose since the start of Pakistan's mass inoculation drive on February 2.

Linus Torvalds was "clearly unamused" by a "humanoid conspiracy theory, and also on its discussion in a Linux kernel topic thread," reports Neowin. They add that Torvalds "weighed in quite heavily with some very strong language, mixed with some biology lessons..."

Here's an excerpt from Torvalds' response (as shared by Slashdot reader Hmmmmmm): Please keep your insane and technically incorrect anti-vax comments to yourself.

You don't know what you are talking about, you don't know what mRNA is, and you're spreading idiotic lies. Maybe you do so unwittingly, because of bad education. Maybe you do so because you've talked to "experts" or watched youtube videos by charlatans that don't know what they are talking about.

But dammit, regardless of where you have gotten your mis-information from, any Linux kernel discussion list isn't going to have your idiotic drivel pass uncontested from me.

Vaccines have saved the lives of literally tens of millions of people.

Just for your edification in case you are actually willing to be educated: mRNA doesn't change your genetic sequence in any way. It is the exact same intermediate - and temporary - kind of material that your cells generate internally all the time as part of your normal cell processes, and all that the mRNA vaccines do is to add a dose their own specialized sequence that then makes your normal cell machinery generate that spike protein so that your body learns how to recognize it.

The half-life of mRNA is a few hours. Any injected mRNA will be all gone from your body in a day or two. It doesn't change anything long-term, except for that natural "your body now knows how to recognize and fight off a new foreign protein" (which then tends to fade over time too, but lasts a lot longer than a few days). And yes, while your body learns to fight off that foreign material, you may feel like shit for a while. That's normal, and it's your natural response to your cells spending resources on learning how to deal with the new threat.

And of the vaccines, the mRNA ones are the most modern, and the most targeted - exactly because they do *not* need to have any of the other genetic material that you traditionally have in a vaccine (ie no need for basically the whole - if weakened - bacterial or virus genetic material). So the mRNA vaccines actually have *less* of that foreign material in them than traditional vaccines do. And a *lot* less than the very real and actual COVID-19 virus that is spreading in your neighborhood.

Honestly, anybody who has told you differently, and who has told you that it changes your genetic material, is simply uneducated. You need to stop believing the anti-vax lies, and you need to start protecting your family and the people around you. Get vaccinated...

Get vaccinated. Stop believing the anti-vax lies.

And if you insist on believing in the crazy conspiracy theories, at least SHUT THE HELL UP about it on Linux kernel discussion lists.

A third member of a panel of outside advisers to the U.S. Food and Drug Administration has resigned in protest over the agency's decision to approve Biogen's Alzheimer's disease treatment despite the committee's recommendation against doing so. Reuters reports: Aaron Kesselheim, a Professor of Medicine at Harvard Medical School who had served on the FDA's advisory committee for nervous system drugs since 2015, told Reuters on Thursday he was stepping down from the panel. "My rationale was that the FDA needs to re-evaluate how it solicits and uses the advisory committees ... because I didn't think that the firm recommendations from the committee in this case ... were appropriately integrated into the decision-making process," Kesselheim said in an email. He cited FDA's decision to approve Sarepta Therapeutic's drug, eteplirsen, for Duchenne muscular dystrophy in 2016 as another example of the regulator approving a drug against the recommendations of its advisory committee.

On Tuesday, a member of the advisory group who voted against the approval, Washington University neurologist Dr. Joel Perlmutter, resigned from the committee, citing the FDA's approval of Aduhelm. Mayo Clinic neurologist Dr. David Knopman said he resigned on Wednesday. The 11-member committee voted nearly unanimously in November that Biogen's drug should not be approved, citing inconclusive evidence that the drug was effective.

PolygamousRanchKid shares a report from Gizmodo: A dose of laughing gas may just help some people with hard-to-treat depression, suggests a new, small clinical trial published Wednesday. The study found that people who inhaled nitrous oxide reported improvements in their depression symptoms afterward. It also found that people felt similar improvements with a smaller dose as they did with a larger one, but experienced substantially fewer side effects. Nitrous oxide (NO) is a colorless, non-flammable gas at room temperature that's long been used as an anesthetic and sometimes as a recreational drug, due to the euphoria and dissociative hallucinations it can cause upon inhalation. But several years ago, Peter Nagele, a researcher and trauma anesthesiologist at the University of Chicago, and his colleagues began looking into nitrous oxide as a potential treatment for depression.

The small trial recruited 28 participants in a crossover design, which is when all the volunteers go through each of the trial's conditions and their responses are compared to one another (as opposed to two or more distinct groups that either take the drug or placebo). The team found that these volunteers on average experienced a greater improvement in depression symptoms when they took the nitrous oxide at either dose than they did after taking the placebo (based on the primary survey they completed) -- an improvement that lasted for up to two weeks. Some doctors and patients had been using generic ketamine, taken through IV, as an experimental depression treatment for years. But Johnson & Johnson didn't fund expensive clinical trials to secure an approval for ketamine as a depression treatment; it instead developed a patentable form taken as a nasal spray, called esketamine. That sort of commercialization isn't something that's possible with nitrous oxide, according to Nagale. The study has been published in the journal Science Translational Medicine.

Dengue fever cases have been cut by 77% in a "groundbreaking" trial that manipulates the mosquitoes that spread it, say scientists. The BBC reports: They used mosquitoes infected with "miraculous" bacteria that reduce the insect's ability to spread dengue. The trial took place in Yogyakarta city, Indonesia, and is being expanded in the hope of eradicating the virus. The World Mosquito Programme team says it could be a solution to a virus that has gone around the world. The trial used mosquitoes infected with Wolbachia bacteria. One of the researchers, Dr Katie Anders, describes them as "naturally miraculous." Wolbachia doesn't harm the mosquito, but it camps out in the same parts of its body that the dengue virus needs to get into. The bacteria compete for resources and make it much harder for dengue virus to replicate, so the mosquito is less likely to cause an infection when it bites again.

The trial used five million mosquito eggs infected with Wolbachia. Eggs were placed in buckets of water in the city every two weeks and the process of building up an infected population of mosquitoes took nine months. Yogyakarta was split into 24 zones and the mosquitoes were released only in half of them. The results, published in the New England Journal of Medicine, showed a 77% reduction in cases and an 86% reduction in people needing hospital care when the insects were released.

The Biden administration is buying 500 million doses of Pfizer's coronavirus vaccine to donate to the world, as the United States dramatically increases its efforts to help vaccinate the global population, the Washington Post reported Wednesday, citing three people familiar with the plans. From the report: President Biden is slated to announce the plan at the G-7 meeting in Britain this week amid growing calls for the United States and other rich countries to play a more substantial role in boosting the global supply of vaccines. Biden told reporters Wednesday as he boarded Air Force One to Europe he would be announcing his global vaccine strategy. The Biden administration previously announced it would share at least 80 million vaccine doses with the world by the end of June. Last week, the White House detailed plans for how it would allocate 25 million doses, with about 19 million of them being shared with Covax, the World Health Organization-backed initiative to distribute vaccine doses around the globe. Roughly 6 million doses would be shared directly with countries experiencing severe coronavirus outbreaks, including India.

For more than a week, an average of about 20 million people have been vaccinated against COVID-19 every day in China. At this rate, the nation would have fully vaccinated the entire UK population in little more than six days. From a report: China now accounts for more than half of the 35 million or so people around the world receiving a COVID-19 shot each day. Zoltan Kis, a chemical engineer in the Future Vaccine Manufacturing Research Hub at Imperial College London, doesn't know of "anything even close to those production scales" for a vaccine. "The manufacturing efforts required in China to reach this high production throughput are tremendous," he says. The majority of doses are of one of two vaccines, both of which have been approved for emergency use worldwide by the World Health Organization (WHO). CoronaVac -- produced by Beijing-based company Sinovac -- showed an efficacy of 51% against symptoms of COVID-19 in clinical trials, and much higher protection against severe disease and death. The second jab was developed in Beijing by state-owned firm Sinopharm and has demonstrated an efficacy of 79% against symptomatic disease and hospitalization.

"A new kind of COVID-19 vaccine could be available as soon as this summer," reports NPR: It's what's known as a protein subunit vaccine. It works somewhat differently from the current crop of vaccines authorized for use in the U.S. but is based on a well-understood technology and doesn't require special refrigeration.

In general, vaccines work by showing people's immune systems something that looks like the virus but really isn't. Consider it an advance warning; if the real virus ever turns up, the immune system is ready to try to squelch it. In the case of the coronavirus, that "something" is one of the proteins in the virus — the spike protein. The vaccines made by Johnson & Johnson, Moderna and Pfizer contain genetic instructions for the spike protein, and it's up to the cells in our bodies to make the protein itself.

The first protein subunit COVID-19 vaccine to become available will likely come from the biotech company, Novavax. In contrast to the three vaccines already authorized in the U.S., it contains the spike protein itself — no need to make it, it's already made — along with an adjuvant that enhances the immune system's response, to make the vaccine even more protective.

Protein subunit vaccines made this way have been around for a while. There are vaccines on the market for hepatitis B and pertussis based on this technology.
And meanwhile, the article points out, there's also another company — the pharmaceutical giant Sanofi — that's also working on its own protein subunit vaccine against the coronavirus.

The American Heart Association is a research-funding nonprofit. One of its publications, The Journal of the American Heart Association, "has concurred with a previous report by the Heart Rhythm Journal which said close contact with an iPhone 12 affected certain implantable cardiac devices," writes Apple Insider. As with that report, the American Heart Association says the effect are solely when the iPhone is on or very near the implant... "Our study demonstrates that magnet reversion mode may be triggered when the iPhone 12 Pro Max is placed directly on the skin over an implantable cardiac device and thus has the potential to inhibit lifesaving therapies," say the report writers in the Journal of the American Heart Association. The testing involved placing the iPhone 12 Pro Max in very close proximity to a series of 11 different pacemakers and defibrillators... The degree of interference did vary across the testing, but all devices were affected. The report says that "the iPhone 12 Pro Max was able to trigger magnetic reversion mode at a distance up to 1.5cm [0.6 inches]."

"Apple Inc, has an advisory stating that the newer generation iPhone 12 does not pose a greater risk for magnet interference when compared to the older generation iPhones," notes the report. "However, our study suggests otherwise as magnet response was demonstrated in 3/3 cases in vivo..."

In January 2021, Apple updated its MagSafe support document to recommend that users keep the iPhone 12 six inches away from any medical implants.

A long read in Wired argues that the mRNA vaccine revolution is just beginning.

CNN explains why scientists are so excited: When the final Phase 3 data came out last November showing the mRNA vaccines made by Pfizer/BioNTech and Moderna were more than 90% effective, Dr. Anthony Fauci had no words. He texted smiley face emojis to a journalist seeking his reaction. This astonishing efficacy has held up in real-world studies in the U.S., Israel and elsewhere. The mRNA technology developed for its speed and flexibility as opposed to expectations it would provide strong protection against an infectious disease has pleased and astonished even those who already advocated for it...

This approach that led to remarkably safe and effective vaccines against a new virus is also showing promise against old enemies such as HIV, and infections that threaten babies and young children, such as respiratory syncytial virus and metapneumovirus. It's being tested as a treatment for cancers, including melanoma and brain tumors. It might offer a new way to treat autoimmune diseases. And it's also being checked out as a possible alternative to gene therapy for intractable conditions such as sickle cell disease.
In fact, Moderna is already working on personalized cancer vaccines, the article points out — and that's just the beginning. Two researchers whose technology underlies both the Modern and BioNTech/Pfizer vaccines are now also working on two vaccines against HIV, another one to prevent genital herpes, and two targeting influenza, including a so-called universal influenza vaccine that could protect against rapidly mutating flu strains, possibly offering years of protection with a single shot.

And researchers have also studied mRNA vaccines to fight Ebola, Zika, rabies and cytomegalovirus.

Type "vaccines" into Amazon's search bar, and its auto-complete suggests "are dangerous" for your search. But that's just part of a larger problem, points out Fast Company (in an article shared by Slashdot reader tedlistens).

For example, Amazon's search results are touting as "best sellers!" many books with some very bad science: Offered by small publishers or self-published through Amazon's platform, the books rehearse the falsehoods and conspiracy theories that fuel vaccine opposition, steepening the impact of the pandemic and slowing a global recovery. They also illustrate how the world's biggest store has become a megaphone for anti-vaccine activists, medical misinformers, and conspiracy theorists, pushing dangerous falsehoods in a medium that carries more apparent legitimacy than just a tweet.

"Without question, Amazon is one of the greatest single promoters of anti-vaccine disinformation, and the world leader in pushing fake anti-vaccine and COVID-19 conspiracy books," says Peter Hotez, a pediatrician and vaccine expert at the Baylor College of Medicine. For years, journalists and researchers have warned of the ways fraudsters, extremists, and conspiracy theorists use Amazon to earn cash and attention. To Hotez, who has devoted much of his career to educating the public about vaccines, the real-world consequences aren't academic. In the U.S. and elsewhere, he says, vaccination efforts are now up against a growing ecosystem of activist groups, foreign manipulators, and digital influencers who "peddle fake books on Amazon...."

Gradually, Amazon has taken a tougher approach to content moderation, and to a seemingly ceaseless onslaught of counterfeits, fraud, defective products, and toxic speech... Despite its sweeps, however, Amazon is still flooded with misinformation, and helping amplify it too: A series of recent studies and a review by Fast Company show the bookstore is boosting misinformation around health-related terms like "autism" or "covid," and nudging customers toward a universe of other conspiracy theory books.

In one audit first published in January, researchers at the University of Washington surveyed Amazon's search results for four dozen terms related to vaccines. Among 38,000 search results and over 16,000 recommendations, they counted nearly 5,000 unique products containing misinformation, or 10.47% of the total. For books, they found that titles deemed misinformative appeared higher in search results than books that debunked their theories. "Overall, our audits suggest that Amazon has a severe vaccine/health misinformation problem exacerbated by its search and recommendation algorithms," write Prerna Juneja and Tanushee Mitra in their paper, presented last month at the CHI Conference on Human Factors in Computing Systems. "Just a single click on an anti-vaccine book could fill your homepage with several other similar anti-vaccine books..." Like any products on Amazon, or any content across social media platforms, anti-vaccine titles also benefit from an algorithmically-powered ranking system. And despite the company's aggressive efforts to battle fraud, it's a system that's still easily manipulated through false reviews...

Much of the uproar about misinformation has focused on Facebook, YouTube, and Twitter, but Amazon's role deserves more attention, says Marc Tuters, an assistant professor of new media at the University of Amsterdam, who helped lead the Infodemic.eu study. The retailer sells half of all the books in the U.S. and its brand is highly trusted by consumers.

"It's kind of embarrassing to say, but the social media app TikTok figured out I had ADHD before I did," writes 23-year-old Australian journalist Matilda Boseley in The Guardian.

"For 23 years my parents, my teachers, my doctor, my psychologist and my own brain all missed the warning signs, yet somehow it only took that app's algorithm a few days to accidentally diagnose me..." Growing up I had always had a nagging feeling that everyone else in the world was coping better than I was. Somehow they could remember appointments and deadlines, they had the discipline to keep an updated planner and they didn't drift off daydreaming in the middle of important conversations... I just felt like there were 10 TVs constantly switched on in my head, and with so much going on, all the small things would fall through the cracks. It wasn't until I downloaded TikTok that I truly considered I might have the disorder.

See, the app is based around the "for you" page which curates a stream of videos for you. It starts out pretty generic, but as you "like" some videos, and quickly scroll past others, the app's algorithm builds a profile of you and your interests. And that profile is scarily accurate sometimes. It genuinely knew me better than I knew myself. What I think happened is that the algorithm noticed that every time a video titled something like "Five little known signs of ADHD in women" showed up on my feed I would watch it, fascinated, all the way to the end.

So, like the dystopian capitalism machine it is, the app showed me more and more of these videos desperate to keep me on the app and extract every possible advertising cent my eyeballs could buy. But, as a side effect, all of a sudden I was seeing ADHD content made by women and for women, for the very first time. It was like someone putting everything that always felt weird in my brain into words. Forgetting something exists if you can't see it could be a problem with "object permanence". Being unable to stand up and tidy my apartment, despite desperately wanting to, might not be laziness; it could be "executive dysfunction". Suddenly it occurred to me, maybe I wasn't somehow just "worse at being a person" than everyone else. Maybe I simply didn't have enough dopamine in my brain. I can't overstate how liberating that felt.

So I booked a doctor's appointment, and three referrals, four months and about $700 later my new psychiatrist looked straight into the webcam and said: "Yes, I think you clearly have ADHD and you've had it for your whole life." I cried from joy when he said it.

Mental health experts told me it wasn't actually that surprising that hearing first-hand accounts of neurodivergence is what finally made the pin drop. In fact, Beyond Blue's lead clinical advisor Dr Grant Blashki said social media could be an extraordinarily powerful tool for increasing what the medical community refer to as "mental health literacy". In fact "learning you have ADHD on TikTok" is now such a common phenomenon that it's become its own meme on the app. There isn't any hard and fast data on the phenomenon but just from my own experience, since telling my friends about my diagnosis, no less than four people have come back to me saying they reckon they might have it too...

At the end of the day I am so grateful for TikTok, and the creators that make ADHD videos. That algorithm has profoundly changed my life, undoubtedly for the better.

Slashdot reader DevNull127 writes: Documents filed by Florida's health department now "confirm two of the core aspects" of a whistleblower complaint filed by fired data manager Rebekah Jones, the Miami Herald reported Friday. "Sworn affidavits from Department of Health leaders acknowledge Jones' often-denied claim that she was told to remove data from public access after questions from the Miami Herald."

And they also report a position statement from the department (filed August 17th) acknowledging something even morning damning. While a team of epidemiologists at the Department of Health had developed data for the state's plan to re-open — their findings were never actually incorporated into that plan.

Reached for comment, a spokesperson for governor Ron DeSantis still insisted to the Herald that "every action taken by Governor DeSantis was data-driven and deliberate."
From the article: But when the Herald requested the data, data analysis, or data model related to reopening under Florida's open records law, the governor's office responded that there were no responsive records... Secrecy was a policy. Staffers were told not to put anything about the pandemic response into writing, according to four Department of Health employees who spoke on the condition of anonymity... Emails and texts reviewed by the Herald show the governor's office worked in coordination with Department of Health "executive leadership" to micromanage everything about the department's public response to the pandemic, from information requests from the press to specific wording and color choice on the Department of Health website and data dashboard. They slow-walked responses to questions on important data points and public records, initially withholding information and data on deaths and infections at nursing homes, state prisons and schools, forcing media organizations to file or threaten lawsuits. Important information that had previously been made public was redacted from medical examiner accounts of COVID-19 fatalities.

At one point the state mischaracterized the extent of Florida's testing backlog by over 50 percent — skewing the information about how many people were getting sick each day — by excluding data from private labs, a fact that was only disclosed in response to questions from the press. Emails show that amid questions about early community spread, data on Florida's earliest potential cases — which dated back to late December 2019 — were hidden from the public by changing "date range of data that was available on the dashboard."

Department of Health staffers interviewed by the Herald described a "hyper-politicized" communications department that often seemed to be trying to match the narrative coming from Washington.
The Herald's article also "delved into the details of the department's operation," writes DevNull127 : For example, the whistleblower complaint of Rebekah Jones quotes the state's deputy health secretary as telling her pointedly that "I once had a data person who said to me, 'you tell me what you want the numbers to be, and I'll make it happen.'"

Or, as Jones later described that interaction to her mother, "They want me to put misleading data up to support that dumb f***'s plan to reopen. And more people are gonna die because [of] this and that's not what I agreed to."

Last Friday the health department's Office of the Inspector General announced they'd found "reasonable cause" to open an investigation into decisions and actions by Department of Health leadership that could "represent an immediate injury to public health."
Meanwhile, Florida officials confirmed Friday night that their health department "will no longer update its Covid-19 dashboard and will suspend daily case and vaccine reports," according to the New York Times. "Officials will instead post weekly updates, becoming the first U.S. state to move to such an infrequent publishing schedule."

Jones had been using that data to continue running her own online dashboard, and posted Friday in lieu of data that the dashboard's operation would now be interrupted "as I work to reformat the website to adjust for these changes...." But she promised to keep trying to help the people of Florida "in whatever capacity I can with the limitations the Department of Health is now putting on public access to this vital health information."

sciencehabit shares a report from Science Magazine: When Chris Mason's daughter was a toddler, he watched, intrigued, as she touched surfaces on the New York City subway. Then, one day, she licked a pole. "There was a clear microbial exchange," says Mason, a geneticist at Weill Cornell Medicine. "I desperately wanted to know what had happened." So he started swabbing the subway, sampling the microbial world that coexists with people in our transit systems. After his 2015 study revealed a wealth of previously unknown species in New York City, other researchers contacted him to contribute. Now, Mason and dozens of collaborators have released their study of subways, buses, elevated trains, and trams in 60 cities worldwide, from Baltimore to Bogota, Colombia, to Seoul, South Korea. They identified thousands of new viruses and bacteria, and found that each city has a unique microbial "fingerprint."

They found that about 45% didn't match any known species: Nearly 11,000 viruses and 1,302 bacteria were new to science. The researchers also found a set of 31 species present in 97% of the samples; these formed what they called a "core" urban microbiome. A further 1145 species were present in more than 70% of samples. Samples taken from surfaces that people touch -- like railings -- were more likely to have bacteria associated with human skin, compared with surfaces like windows. Other common species in the mix were bacteria often found in soil, water, air, and dust. But the researchers also found species that were less widespread. Those gave each city a unique microbiomeâ"and helped the researchers predict, with 88% accuracy, which city random samples came from, they report today in Cell.

The study's main value isn't in its findings (which are mapped here) so much as its open data, available at metagraph.ethz.ch, says Noah Fierer, a microbiologist at the University of Colorado, Boulder, who was not involved with the research. That will give other researchers the chance to delve into new questions. "Different cities have different microbial communities," Fierer says. "That's not super surprising. The question for me is, why?" Mason sees an opportunity for "awe and excitement about mass transit systems as a source of unexplored and phenomenal biodiversity." Newly discovered species have potential for drug research, he says, and wide-scale mapping and monitoring of urban microbiomes would be a boon for public health, helping researchers spot emerging pathogens early.

Immunity to the coronavirus lasts at least a year, possibly a lifetime, improving over time especially after vaccination, according to two new studies. The findings may help put to rest lingering fears that protection against the virus will be short-lived. From a report: Together, the studies suggest that most people who have recovered from Covid-19 and who were later immunized will not need boosters. Vaccinated people who were never infected most likely will need the shots, however, as will a minority who were infected but did not produce a robust immune response. Both reports looked at people who had been exposed to the coronavirus about a year earlier. Cells that retain a memory of the virus persist in the bone marrow and may churn out antibodies whenever needed, according to one of the studies, published on Monday in the journal Nature. The other study, posted online at BioRxiv, a site for biology research, found that these so-called memory B cells continue to mature and strengthen for at least 12 months after the initial infection.

"The papers are consistent with the growing body of literature that suggests that immunity elicited by infection and vaccination for SARS-CoV-2 appears to be long-lived," said Scott Hensley, an immunologist at the University of Pennsylvania who was not involved in the research. The studies may soothe fears that immunity to the virus is transient, as is the case with coronaviruses that cause common colds. But those viruses change significantly every few years, Dr. Hensley said. "The reason we get infected with common coronaviruses repetitively throughout life might have much more to do with variation of these viruses rather than immunity," he said. In fact, memory B cells produced in response to infection with SARS-CoV-2 and enhanced with vaccination are so potent that they thwart even variants of the virus, negating the need for boosters, according to Michel Nussenzweig, an immunologist at Rockefeller University in New York who led the study on memory maturation.