Medicine

Researchers Say AI Transcription Tool Used In Hospitals Invents Things (apnews.com) 33

Longtime Slashdot reader AmiMoJo shares a report from the Associated Press: Tech behemoth OpenAI has touted its artificial intelligence-powered transcription tool Whisper as having near "human level robustness and accuracy." But Whisper has a major flaw: It is prone to making up chunks of text or even entire sentences, according to interviews with more than a dozen software engineers, developers and academic researchers. Those experts said some of the invented text -- known in the industry as hallucinations -- can include racial commentary, violent rhetoric and even imagined medical treatments. Experts said that such fabrications are problematic because Whisper is being used in a slew of industries worldwide to translate and transcribe interviews, generate text in popular consumer technologies and create subtitles for videos.

The full extent of the problem is difficult to discern, but researchers and engineers said they frequently have come across Whisper's hallucinations in their work. A University of Michigan researcher conducting a study of public meetings, for example, said he found hallucinations in eight out of every 10 audio transcriptions he inspected, before he started trying to improve the model. A machine learning engineer said he initially discovered hallucinations in about half of the over 100 hours of Whisper transcriptions he analyzed. A third developer said he found hallucinations in nearly every one of the 26,000 transcripts he created with Whisper. The problems persist even in well-recorded, short audio samples. A recent study by computer scientists uncovered 187 hallucinations in more than 13,000 clear audio snippets they examined. That trend would lead to tens of thousands of faulty transcriptions over millions of recordings, researchers said.
Further reading: AI Tool Cuts Unexpected Deaths In Hospital By 26%, Canadian Study Finds
United Kingdom

'Operating in the Stone Age': NHS Staff's Daily Struggle With Outdated Tech 113

The Financial Times: In the paediatric centre at one of London's largest hospitals, doctors are confounded each day by a ward computer that is not connected to a printer. The computer is used for managing the daily list of patients. Doctors can only access and update the list, using one shared account. So twice a day, two doctors on the ward said one of them had to log in to this computer, update the patient list, send the list to themselves via NHS email, and then log in to another nearby computer to print it off for the team. "I am at a top London hospital and yet at times I feel as though we are operating in the Stone Age," said one paediatrician on the ward.

Tackling the frustrating delays caused by outdated technology [Editor's note: non-paywalled link] is one of health secretary Wes Streeting and Prime Minister Sir Keir Starmer's core missions, having vowed to shift the service "from an analogue to a digital NHS." The monumental task of moving the world's largest publicly funded health service into the digital age is not lost on doctors working on the frontline of the NHS. While many sectors of the economy have been "radically reshaped" by technology in recent years, a landmark report into the state of the health service in England last month concluded that the NHS stood "in the foothills of digital transformation."

But doctors and nurses point out that the basic infrastructure needs to be brought up to a minimum standard, given significant regional variations between hospitals, before politicians extol the virtues of cutting-edge tech. "Some of us just want the printers to work," noted one NHS hospital doctor. "The complete flip-a-coin nature of how equipped your hospital is is mind-boggling," they added. "I have worked in hospitals that are at least 12 years behind others." A report published in 2022 by the British Medical Association, the UK's main doctors' union, estimated that doctors in England lost 13.5mn working hours a year as a consequence of "inadequate IT systems and equipment." One reason for the outdated infrastructure is that the country has spent almost $48bn less than its peers -- such as Germany, France, Australia -- on health assets since the 2010s, according to a government-commissioned study by Lord Ara Darzi last month.
Medicine

Egypt Declared Malaria-Free After Century of Work To Defeat Disease (semafor.com) 36

Egypt was declared malaria-free by the World Health Organization, after nearly a century of work to eradicate the disease in the country. From a report: Egypt saw 3 million cases a year in the 1940s, and the Aswan Dam's development in the 1960s created new bodies of standing water for the mosquitoes to breed in, but by 2001 the disease was "firmly under control," according to the WHO. "The disease that plagued pharaohs now belongs to [Egypt's] history," the WHO's chief said. It's the 44th country to be certified, but the wider battle against malaria goes on: The mosquito-borne disease still kills around 600,000 people a year, the large majority of them children in sub-Saharan Africa.
Medicine

Serious Infections Linked to Dementia Risk, Study Shows (msn.com) 18

"Getting sick feels bad in the moment," reports the Washington Post, "and may affect your brain in the longer term." A new study published in Nature Aging adds to growing evidence that severe infections, including flu, herpes and respiratory tract infections, are linked to accelerated brain atrophy and increased risk of dementia years later. It also hints at the biological drivers that may contribute to neurodegenerative disease.

The current research is a "leap beyond previous studies that had already associated infection with susceptibility to Alzheimer's disease" and provides a "useful dataset," said Rudy Tanzi, a professor of neurology at Harvard Medical School and the director of the McCance Center for Brain Health at Massachusetts General Hospital. Other recent studies have found that the flu shot and the shingles vaccine reduce the risk of subsequent dementia in those who get them. Severe infections have also been linked to subsequent strokes and heart attacks.

"Big infection, big immune response — not good for the brain," said one of the study's co-authors (Keenan Walker, a tenure-track investigator and the director of the Multimodal Imaging of Neurodegenerative Disease Unit at the National Institute on Aging).

And the article also includes this quote from Kristen Funk, an assistant professor of biological sciences at the University of North Carolina at Charlotte (who studies neuroinflammation in neuroinfectious and neurodegenerative diseases). "They really found that there's a range of infections that are associated with this brain atrophy, associated with this cognitive decline." In turn, most of these infections associated with brain atrophy seem to be risk factors for dementia, according to the researchers' analyses of the UK Biobank data of 495,896 subjects and a Finnish dataset of 273,132 subjects. They found that having a history of infections was associated with an increased risk for Alzheimer's disease years later. The increased risk was even higher for vascular dementia, which is the second-most-common dementia diagnosis after Alzheimer's disease and caused by restriction of blood to the brain...

More-minor infections are not cause for alarm since the data was drawn from patients who had a hospital record of their infections, indicating more-severe cases, experts say.

And speaking of infections, the Post also published an interesting guest column by Dr. Mikkael A. Sekeres, division chief for hematology and medicine professor at the University of Miami's cancer center: A recent report from the American Association for Cancer Research attributed 13 percent of cancer cases worldwide to infections. Some estimates run as high as 20 percent, with particularly high rates of infection-related cancers in developing countries. Infectious agents linked to cancer include bacteria, such as Helicobacter pylori (H. pylori), and viruses, such as human papillomavirus (HPV), Epstein-Barr virus (EBV), and hepatitis B and C.

But keep in mind that an exceedingly small percentage of infected people develop cancer...

Cellphones

All Mobile Phones Must Be Hearing Aid Compatible Under New FCC Rules (techcrunch.com) 17

In a press release today, the FCC said it is requiring all mobile phones sold in the U.S. to be compatible with hearing aids. TechCrunch reports: The FCC has not yet issued a specific timeline for compliance, only noting that the rules will be fully in effect "after a transition period." The rules discourage handset makers from instituting proprietary Bluetooth coupling, which could limit device compatibility with over-the-counter hearing aids. Under the new rules, companies will be required to note on their website if a given handset is compatible with hearing aids. Two years ago, the FDA announced that hearing aids would no longer require a prescription. The agency also recently approved Apple AirPods as hearing aids.
Businesses

Startup Can Identify Deepfake Video In Real Time (wired.com) 28

An anonymous reader quotes a report from Wired: Real-time video deepfakes are a growing threat for governments, businesses, and individuals. Recently, the chairman of the US Senate Committee on Foreign Relations mistakenly took a video call with someone pretending to be a Ukrainian official. An international engineering company lost millions of dollars earlier in 2024 when one employee was tricked by a deepfake video call. Also, romance scams targeting everyday individuals have employed similar techniques. "It's probably only a matter of months before we're going to start seeing an explosion of deepfake video, face-to-face fraud," says Ben Colman, CEO and cofounder at Reality Defender. When it comes to video calls, especially in high-stakes situations, seeing should not be believing.

The startup is laser-focused on partnering with business and government clients to help thwart AI-powered deepfakes. Even with this core mission, Colman doesn't want his company to be seen as more broadly standing against artificial intelligence developments. "We're very pro-AI," he says. "We think that 99.999 percent of use cases are transformational -- for medicine, for productivity, for creativity -- but in these kinds of very, very small edge cases the risks are disproportionately bad." Reality Defender's plan for the real-time detector is to start with a plug-in for Zoom that can make active predictions about whether others on a video call are real or AI-powered impersonations. The company is currently working on benchmarking the tool to determine how accurately it discerns real video participants from fake ones. Unfortunately, it's not something you'll likely be able to try out soon. The new software feature will only be available in beta for some of the startup's clients.

As Reality Defender works to improve the detection accuracy of its models, Colman says that access to more data is a critical challenge to overcome -- a common refrain from the current batch of AI-focused startups. He's hopeful more partnerships will fill in these gaps, and without specifics, hints at multiple new deals likely coming next year. After ElevenLabs was tied to a deepfake voice call of US president Joe Biden, the AI-audio startup struck a deal with Reality Defender to mitigate potential misuse. [...] "We don't ask my 80-year-old mother to flag ransomware in an email," says Colman. "Because she's not a computer science expert." In the future, it's possible real-time video authentication, if AI detection continues to improve and shows to be reliably accurate, will be as taken for granted as that malware scanner quietly humming along in the background of your email inbox.

Medicine

Are Standing Desks Actually Bad For Your Health? 140

A new study counters the widely held belief that standing desks are good for your health, discovering that it does not reduce the risk of diseases such as stroke and heart failure. In fact, it "found that being on your feet for more than two hours a day may increase the risk of developing problems such as deep vein thrombosis and varicose veins," reports The Guardian. The findings have been published in the International Journal of Epidemiology. From the report: To establish if standing provided any health benefits, the researchers studied data from 83,013 adults who are part of the UK Biobank health records database. These people did not have heart disease at the start of the study and wore devices on their wrists to track movement. The team found that for every extra 30 minutes spent standing beyond two hours, the risk of circulatory disease increased by 11%. Standing was not found to reduce the risk of heart conditions such as stroke, heart failure and coronary heart disease, the researchers said. "The key takeaway is that standing for too long will not offset an otherwise sedentary lifestyle and could be risky for some people in terms of circulatory health," said Dr Matthew Ahmadi, of the University of Sydney's faculty of medicine and health. "We found that standing more does not improve cardiovascular health over the long-term and increases the risk of circulatory issues."
Medicine

Human Sense of Smell Is Faster Than Previously Thought, New Study Suggests 26

A new study reveals that the human sense of smell is far more sensitive than previously thought, capable of distinguishing odors and their sequences within just 60 milliseconds. CNN reports: In a single sniff, the human sense of smell can distinguish odors within a fraction of a second, working at a level of sensitivity that is "on par" with how our brains perceive color, "refuting the widely held belief that olfaction is our slow sense," a new study finds. Humans also can discern between various sequences of odors -- distinguishing a sequence of "A" before "B" from sequence "B" before "A" -- when the interval between odorant A and odorant B is merely 60 milliseconds, according to the study, published Monday in the journal Nature Human Behavior. [...]

The new findings challenge previous research in which the timing it took to discriminate between odor sequences was around 1,200 milliseconds, Dr. Dmitry Rinberg, a professor in the Department of Neuroscience and Physiology at NYU Langone Health in New York, wrote in an editorial accompanying the study in Nature Human Behavior. "The timing of individual notes in music is essential for conveying meaning and beauty in a melody, and the human ear is very sensitive to this. However, temporal sensitivity is not limited to hearing: our sense of smell can also perceive small temporal changes in odor presentations," he wrote. "Similar to how timing affects the perception of notes in a melody, the timing of individual components in a complex odor mixture that reaches the nose may be crucial for our perception of the olfactory world."

The ability to tell apart odors within a single sniff might be an important way in which animals detect both what a smell is and where it might be in space, said Dr. Sandeep Robert Datta, a professor in the Department of Neurobiology at Harvard Medical School, who was not involved in the new study. "The demonstration that humans can tell apart smells as they change within a sniff is a powerful demonstration that timing is important for smell across species, and therefore is a general principle underlying olfactory function. In addition, this study sheds important light on the mysterious mechanisms that support human odor perception," Datta wrote in an email. "The study of human olfaction has historically lagged that of vision and hearing, because as humans we think of ourselves as visual creatures that largely use speech to communicate," he said, adding that the new study helps "fill a critical gap in our understanding of how we as humans smell."
Medicine

25% of Adults Suspect Undiagnosed ADHD (neurosciencenews.com) 154

An anonymous reader quotes a report from Neuroscience News: Attention deficit/hyperactivity disorder -- also known as ADHD -- is typically thought of as a childhood condition. But more adults are realizing that their struggles with attention, focus and restlessness could in fact be undiagnosed ADHD, thanks in large part to trending social media videos racking up millions of views. A new national survey of 1,000 American adults commissioned by The Ohio State University Wexner Medical Center and College of Medicine finds that 25% of adults now suspect they may have undiagnosed ADHD. But what worries mental health experts is that only 13% of survey respondents have shared their suspicions with their doctor. That's raising concerns about the consequences of self-diagnosis leading to incorrect treatment.

"Anxiety, depression and ADHD -- all these things can look a lot alike, but the wrong treatment can make things worse instead of helping that person feel better and improving their functioning," said psychologist Justin Barterian, PhD, clinical assistant professor in Ohio State's Department of Psychiatry and Behavioral Health. An estimated 4.4% of people ages 18 to 44 have ADHD, and some people aren't diagnosed until they're older, Barterian said. "There's definitely more awareness of how it can continue to affect folks into adulthood and a lot of people who are realizing, once their kids have been diagnosed, that they fit these symptoms as well, given that it's a genetic disorder," Barterian said. The survey found that younger adults are more likely to believe they have undiagnosed ADHD than older generations, and they're also more likely to do something about it. Barterian said that should include seeing a medical professional, usually their primary care provider, to receive a referral to a mental health expert to be thoroughly evaluated, accurately diagnosed and effectively treated.

Medicine

The Crackdown on Compounded GLP-1 Meds Has Begun (wired.com) 53

Eli Lilly and Novo Nordisk are leading efforts to curb the sale of compounded GLP-1 medications. Lilly has issued hundreds of cease-and-desist letters to entities selling compounded tirzepatide, following the end of its FDA-declared shortage. Novo Nordisk, whose semaglutide drugs remain in shortage, is taking a different approach. The company published a peer-reviewed study in Pharmaceutical Research, highlighting quality concerns in compounded semaglutide samples, including lower-than-claimed strength and banned ingredients. These actions signal a broader industry pushback against compounders who entered the market during drug shortages. Wired adds: With mounting evidence that GLP-1s like tirzepatide are an effective treatment for other ailments beyond obesity and diabetes -- including addiction and Parkinson's disease -- demand is only expected to increase. It remains to be seen whether the pharmaceutical companies will be able to keep pace with the demand or if the meds will go back into shortage and compounders will be able to bound back into the market.
Medicine

Rises In Life Expectancy Have Slowed Dramatically, Analysis Finds 97

The rapid increases in life expectancy seen in the 20th century have slowed significantly, according to a new analysis published in the journal Nature. The Guardian reports: According to the study, children born recently in regions with the oldest people are far from likely to become centenarians. At best, the researchers predict 15% of females and 5% of males in the oldest-living areas will reach 100 this century. "If you're planning for retirement, it's probably not a good idea to assume you're going to make it to 100," said Jay Olshansky, professor of epidemiology and biostatistics at the University of Illinois at Chicago. "You'd probably have to work for at least 10 years longer than you'd think. And you want to enjoy the last phase of your life, you don't necessarily want to spend it working to save for time you're not going to experience."

Advances in public health and medicine sparked a longevity revolution in the 20th century. In the previous 2,000 years, life expectancy crept up, on average, one year every century or two. In the 20th century, average life expectancy rocketed, with people gaining an extra three years every decade. For the latest study, Olshansky delved into national statistics from the US and nine regions with the highest life expectancies, focusing on 1990 to 2019, before the Covid pandemic struck. The data from Hong Kong, Japan, South Korea, Australia, France, Italy, Switzerland, Sweden, and Spain showed that rises in life expectancy had slowed dramatically. In the US, life expectancy fell [T]he researchers describe how on average, life expectancy in the longest-living regions rose only 6.5 years between 1990 and 2019. They predict that girls born recently in the regions have only a 5.3% chance of reaching 100 years old, while boys have a 1.8% chance.

"In the modern era we have, through public health and medicine, manufactured decades of life that otherwise would not exist," Olshansky said. "These gains must slow down. The longevity game we're playing today is different to the longevity game we played a century ago when we were saving infants and children and women of child-bearing age and the gains in life expectancy were large. Now the gains are small because we're saving people in their 60s, 70s, 80s, and 90s." Olshansky said it would take radical new treatments that slow ageing, the greatest risk factor for many diseases, to achieve another longevity revolution. Research in the field is afoot with a dozen or so drugs shown to increase the lifespan of mice.
Science

Google DeepMind Scientists Win Nobel Chemistry Prize for Work on Proteins (npr.org) 15

Three scientists won the 2024 Nobel Prize in Chemistry on Wednesday for their groundbreaking work in predicting and designing protein structures, the Royal Swedish Academy of Sciences announced in Stockholm. David Baker of the University of Washington shares the prize with Demis Hassabis and John Jumper of Google DeepMind. Baker pioneered the creation of novel proteins, while Hassabis and Jumper developed AlphaFold, an AI model that predicts protein structures from amino acid sequences.

The laureates will split the 11 million Swedish kronor ($1 million) award for their contributions to computational protein design and structure prediction. Baker's team has produced proteins with applications in medicine and materials science since his initial breakthrough in 2003. Hassabis and Jumper's AlphaFold, announced in 2020, has predicted structures for nearly all 200 million known proteins. "We glimpsed at the beginning that it might be possible to create a whole new world of proteins that address a lot of the problems faced by humans in the 21st century," Baker said at a press briefing.

"Now it's becoming possible," Heiner Linke, chair of the Nobel chemistry committee, called the discoveries "spectacular," noting they fulfilled a 50-year-old dream of predicting protein structures from amino acid sequences. The breakthroughs have wide-ranging implications, from understanding antibiotic resistance to developing enzymes that decompose plastic. Over 2 million researchers worldwide have already utilized AlphaFold in various applications.
United States

MicroRNA Pioneers Win Nobel Prize in Medicine (nobelprize.org) 5

American scientists Victor Ambros and Gary Ruvkun won the Nobel Prize in Physiology or Medicine on Monday for discovering microRNA, tiny molecules that regulate gene expression. Their groundbreaking work in the 1990s revealed a new layer of genetic control, opening fresh avenues for understanding human development and disease.

Ambros first identified microRNA in 1993, while Ruvkun later found similar molecules in humans and other species. These RNA fragments, about 100 times smaller than typical messenger RNA, can silence genes and fine-tune protein production. The discovery has spurred research into potential treatments for cancer, heart disease, and neurological disorders. Several biotechnology companies are now developing drugs that target or mimic microRNAs.
Medicine

Bird Flu Fears Stoke the Race for an mRNA Flu Vaccine 236

Concern over potential human-to-human transmission of bird flu has risen after six Missouri healthcare workers developed mild respiratory symptoms following contact with a patient infected with H5N1. The CDC reports only the original patient has tested positive for the virus. Scientists are ramping up efforts to develop mRNA vaccines against H5N1, with researchers at the University of Pennsylvania and major pharmaceutical companies like Moderna, Pfizer, and GSK leading the charge. While mRNA technology offers rapid vaccine production, clinical trials have shown mixed results, particularly against influenza B strains. Wired adds: [...] Traditionally, flu vaccines contain inactivated viruses that are grown in hens' eggs. This works reasonably well, but it takes a long time to make such jabs, which means health authorities have to publish their predictions about which strains of flu will be circulating during the upcoming winter well in advance. If you could manufacture vaccines more quickly, you could make more accurate predictions nearer to flu season.

Not only that, researchers hope that a single mRNA shot could one day target 20 or more strains of flu at once, relieving the need for some of this guesswork. Scher's colleagues are working on such a "universal" flu vaccine. With clinical trials ongoing, it's still early days. Sheena Cruickshank, an immunologist at the University of Manchester, has watched reports about emerging mRNA flu jabs with interest but says that questions remain. "We don't yet know how long-lasting the immunity they produce is," she says. Michael Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota, concurs, though he notes that all flu jabs, regardless of how they are made, have a waning immunity problem -- your protection could decline by around 10 percent every month following injection.
Medicine

Cheetos Food Dye Turns Mice Transparent (nypost.com) 44

Researchers have discovered that a popular food dye used in Cheetos "alters the optical qualities of skin, allowing light to pass through (Source paywalled; alternative source)," according to the Wall Street Journal. Larger doses of the dye used on humans could make searching veins for blood draw easier. From a report: Tartrazine, the yellowing agent for the "dangerously cheesy" snack, was tested on the stomachs and heads of mice -- with surprising results. Researchers were even able to see muscle pulsations and blood vessels in their brains, the Wall Street Journal reported.

How does this ultimate magic trick work? It has to do with how cells are comprised of membranes that hold fats in a watery style, the outlet stated. The fats and water manage light differently. In this case, when the dye is applied, it causes light to pass through when it hits their cells. Thus, ta-da! the transparent opacity of invisible mice skin.
The findings have been published in the journal Science.
Medicine

America's FDA Approves First New Drug for Schizophrenia in Over 30 Years (go.com) 65

Thursday America's Food and Drug Administration approved Cobenfy, "the first new drug to treat people with schizophrenia in more than 30 years," reports ABC News: Most schizophrenia medications, broadly known as antipsychotics, work by changing dopamine levels, a brain chemical that affects mood, motivation, and thinking [according to Jelena Kunovac, MD, a board-certified psychiatrist and adjunct assistant professor at the University of Nevada, Las Vegas, in the Department of Psychiatry]. Cobenfy takes a different approach by adjusting acetylcholine, another brain chemical that aids memory, learning and attention, she said. By focusing on acetylcholine instead of dopamine, Cobenfy may reduce schizophrenia symptoms while avoiding common side effects like weight gain, drowsiness and movement disorders, clinical trials suggest. These side effects often become so severe and unpleasant that, in some studies mirroring real-world challenges, many patients stopped treatment within 18 months of starting it.

In clinical trials, only 6% of patients stopped taking Cobenfy due to side effects, noted Dr. Samit Hirawat, chief medical officer at Bristol Myers Squibb. "That's a significant improvement over the 20-30% seen with older antipsychotic drugs," he added...

Schizophrenia is a mental health disorder that affects about 24 million people worldwide, or roughly one in 300 people, according to the World Health Organization.

"Studies for additional therapeutic uses, including the treatment of Alzheimer's disease and bipolar disorder, are also underway."
Medicine

Alcohol Can Increase Your Cancer Risk, Researchers Find (cbsnews.com) 93

The world's oldest and largest cancer research association "found excessive levels of alcohol consumption increase the risk for six different types of cancer," reports CBS News: "Some of this is happening through chronic inflammation. We also know that alcohol changes the microbiome, so those are the bacteria that live in your gut, and that can also increase the risk," Dr. Céline Gounder, CBS News medical contributor and editor-at-large for public health at KFF Health News, recently said on "CBS Mornings."

But how much is too much when it comes to drinking? We asked experts what to know. "Excessive levels of alcohol" equates to about three or more drinks per day for women and four or more drinks per day for men, Gounder said... Other studies have shown, however, there is no "safe amount" of alcohol, Gounder said, particularly if you have underlying medical conditions. "If you don't drink, don't start drinking. If you do drink, really try to keep it within moderation," she said.

Dr. Amy Commander, medical director of the Mass General Cancer Center specializing in breast cancer, told CBS News alcohol is the third leading modifiable risk factor that can increase cancer risk after accounting for cigarette smoking and excess body weight. [Other factors include physical inactivity — and diet]. "There really isn't a safe amount of alcohol for consumption," she said. "In fact, it's best to not drink alcohol at all, but that is obviously hard for many people. So I think it's really important for individuals to just be mindful of their alcohol consumption and certainly drink less."

The article also includes an interesting statistic from the association's latest Cancer Progress Report: from 1991 to 2021 there's been a 33% reduction in overall cancer deaths in the U.S. That's 4.1 million lives saved — roughly 136,667 lives saved each year.

"So that is hopeful," Commander said, adding that when it comes to preventing cancer, alcohol is just "one piece of the puzzle."
Power

Paralyzed Jockey Loses Ability To Walk After Manufacturer Refuses To Fix Battery For His $100,000 Exoskeleton 147

An anonymous reader quotes a report from 404 Media: After a horseback riding accident left him paralyzed from the waist down in 2009, former jockey Michael Straight learned to walk again with the help of a $100,000 ReWalk Personal exoskeleton. Earlier this month, that exoskeleton broke because of a malfunctioning piece of wiring in an accompanying watch that makes the exoskeleton work. The manufacturer refused to fix it, saying the machine was now too old to be serviced, and Straight once again couldn't walk anymore. "After 371,091 steps my exoskeleton is being retired after 10 years of unbelievable physical therapy," Straight posted on Facebook on September 16. "The reasons [sic] why it has stopped is a pathetic excuse for a bad company to try and make more money. The reason it stopped is because of a battery in the watch I wear to operate the machine. I called thinking it was no big deal, yet I was told they stopped working on any machine that was 5 years or older. I find it very hard to believe after paying nearly $100,000 for the machine and training that a $20 battery for the watch is the reason I can't walk anymore?"

Straight's experience is a nightmare scenario that highlights what happens when companies decide to stop supporting their products and do not actively support independent repair. It's also what happens without the protection of right to repair legislation that requires manufacturers to make repair parts, guides, and tools available to the general public. Specifically, a connection wire became desoldered from the battery in a watch that connects to the exoskeleton: "It's not the actual battery, but it's the little green connection piece we need to be the right fit and that's been our problem," Straight posted on Facebook. Straight's personal exoskeleton was broken for two months, he said in a video on Facebook. He was eventually able to get the device fixed after attention from an article in the Paulick Report, a website about the horse industry, and a spot on local TV. "It took me two months, and I got no results," he said in the video. With social media and news attention, "it only took you all four days, and look at the results," he said earlier this week while standing in the exoskeleton.
"This is the dystopian nightmare that we've kind of entered in, where the manufacturer perspective on products is that their responsibility completely ends when it hands it over to a customer. That's not good enough for a device like this, but it's also the same thing we see up and down with every single product," Nathan Proctor, head of citizen rights group US PIRG's right to repair project told 404 Media. "People need to be able to fix things, there needs to be a plan in place. A $100,000 product you can only use as long as the battery lasts, that's enraging. We should not have to tolerate a society where this happens."

"We have all this technology we release into the wild and it changes people's lives, but there's no long-term thinking. Manufacturers currently have no legal obligation to support the equipment indefinitely and there's no requirements that they publish sufficient documentation to allow others to do it," Proctor said. "We need to set minimum standards for documentation so that, even if a company goes bankrupt or falls off the face of the earth, a technician with sufficient knowledge can fix it."
AI

Microsoft Claims Its New Tool Can Correct AI Hallucinations 50

An anonymous reader quotes a report from TechCrunch: Microsoft today revealed Correction, a service that attempts to automatically revise AI-generated text that's factually wrong. Correction first flags text that may be erroneous -- say, a summary of a company's quarterly earnings call that possibly has misattributed quotes -- then fact-checks it by comparing the text with a source of truth (e.g. uploaded transcripts). Correction, available as part of Microsoft's Azure AI Content Safety API (in preview for now), can be used with any text-generating AI model, including Meta's Llama and OpenAI's GPT-4o.

"Correction is powered by a new process of utilizing small language models and large language models to align outputs with grounding documents," a Microsoft spokesperson told TechCrunch. "We hope this new feature supports builders and users of generative AI in fields such as medicine, where application developers determine the accuracy of responses to be of significant importance."
Experts caution that this tool doesn't address the root cause of hallucinations. "Microsoft's solution is a pair of cross-referencing, copy-editor-esque meta models designed to highlight and rewrite hallucinations," reports TechCrunch. "A classifier model looks for possibly incorrect, fabricated, or irrelevant snippets of AI-generated text (hallucinations). If it detects hallucinations, the classifier ropes in a second model, a language model, that tries to correct for the hallucinations in accordance with specified 'grounding documents.'"

Os Keyes, a PhD candidate at the University of Washington who studies the ethical impact of emerging tech, has doubts about this. "It might reduce some problems," they said, "But it's also going to generate new ones. After all, Correction's hallucination detection library is also presumably capable of hallucinating." Mike Cook, a research fellow at Queen Mary University specializing in AI, added that the tool threatens to compound the trust and explainability issues around AI. "Microsoft, like OpenAI and Google, have created this issue where models are being relied upon in scenarios where they are frequently wrong," he said. "What Microsoft is doing now is repeating the mistake at a higher level. Let's say this takes us from 90% safety to 99% safety -- the issue was never really in that 9%. It's always going to be in the 1% of mistakes we're not yet detecting."
Medicine

America's FTC Sues Insulin Middlemen Who 'Artificially Inflated' Drug Price (npr.org) 124

Friday America's Federal Trade Commission brought action against three companies for "anticompetitive and unfair" practices "that have artificially inflated the list price of insulin."

For years, many of the millions of Americans who need insulin to survive "have been forced to pay exorbitant prices for a product that's inexpensive to make," writes NPR. "Now, the federal government is targeting one part of the system behind high insulin prices." While out-of-pocket costs have gone down for many people to $35 a month, questions remain on how the drug became so expensive in the first place. In a new lawsuit filed Friday, the Federal Trade Commission said it's going after one link in the chain: pharmacy benefit managers. The FTC brought action against the top pharmacy benefit managers (PBMs) — CVS Health's Caremark Rx, Cigna's Express Scripts, and United Health Group's OptumRx — saying the companies created a "perverse drug rebate system" that artificially inflates the cost of insulin. If the suit is successful, it could further drive down costs for patients at the pharmacy counter.

PBMs are essentially the middlemen between drug manufacturers and insurance providers. Their job is to reduce drug prices. But the process is complex and opaque, and critics say they're actually driving prices up for patients. The FTC said a big issue is that PBMs' revenue is tied to rebates and fees — which are based on a percentage of a drug's list price. Essentially, in the case of insulin, when the drug costed more, it generated higher rebates and fees for PBMs. "Even when lower list price insulins became available that could have been more affordable for vulnerable patients, the PBMs systemically excluded them in favor of high list price, highly rebated insulin products," the FTC said in a press release on Friday.

The three PBMs named in the FTC lawsuit make up about 80% of the market. According to the suit, the PBMs collected billions of dollars in rebates and fees while insulin became increasingly unaffordable. Over the last two decades, the cost of the lifesaving drug shot up 600% — forcing many Americans with diabetes to ration their medication and jeopardize their health. In 2019, one 1 of 4 insulin patients was unable to afford their medication, according to the FTC. Some people have died.

The FTC's statement says the companies "have abused their economic power by rigging pharmaceutical supply chain competition in their favor, forcing patients to pay more for life-saving medication... While PBM respondents collected billions in rebates and associated fees according to the complaint, by 2019 one out of every four insulin patients was unable to afford their medication..."

"[A]ll drug manufacturers should be on notice that their participation in the type of conduct challenged here raises serious concerns, and that the Bureau of Competition may recommend suing drug manufacturers in any future enforcement actions."

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